Overview

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors that have a KRAS G12C mutation.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Mirati Therapeutics Inc.
Treatments:
Adagrasib
Afatinib
Cetuximab
Pembrolizumab