Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali

• Status: Unknown status
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The main objective is to study the pharmacokinetics, pharmacodynamics and tolerability of the decoction of the aerial parts of Argemone mexicana (AM), administered in healthy volunteers.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Bamako
• Collaborator: University of Geneva, Switzerland
• Treatments: Antimalarials

Criteria

Inclusion Criteria:

• age of 18-50 years old;

• be in good general health;

• be available for the duration of the study;

• agreement to participate in the study

• be a resident of the village known study;

• acceptance of the conservation laboratory specimens for future research.

Exclusion Criteria:

• Plasmodium falciparum infection with clinical manifestations;

• Presence of severe or complicated malaria;

• Acute medical condition;

• Any other medical condition that requires medical attention inconsistent with the study or interfere with the study;

• Severe medical conditions;

• Allergy to the product of the study,

• Pregnant women or nursing

• Taking a derivative product of the study or other known antimalarial within 14 days before enrollment.

• Refusal to participate