Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC)
Status:
Completed
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
This phase 2 trial is studying whether giving a combination of docetaxel, cisplatin, and
fluorouracil chemotherapy followed by the combination of cisplatin with radiation therapy
works in treating patients with advanced nasopharyngeal cancer. Drugs used in chemotherapy,
such as docetaxel, cisplatin, and fluorouracil, work in different ways to stop the growth of
tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy
uses high-energy x-rays to kill tumor cells. Specialized radiation therapy that delivers a
high dose of radiation directly to the tumor may kill more tumor cells and cause less damage
to normal tissue. Giving combination chemotherapy together with radiation therapy may kill
more tumor cells.