Overview

Phase 2 Trial of Pertuzumab and Trastuzumab With Weekly Paclitaxel and Chemotherapy for HER2 Positive Breast Cancer

Status:
Completed
Trial end date:
2018-08-01
Target enrollment:
Participant gender:
Summary
The main goal of this clinical trial is to test if adding pertuzumab (Perjeta), improves the anticancer activity of the combination chemotherapy regimen of trastuzumab (Herceptin) concomitant with paclitaxel, 5-fluorouracil, epirubicin, and cyclophosphamide (T-FEC). The study will also test the safety of this therapy.
Phase:
Phase 2
Details
Lead Sponsor:
Lajos Pusztai
Yale University
Collaborator:
Genentech, Inc.
Treatments:
Albumin-Bound Paclitaxel
Cyclophosphamide
Epirubicin
Fluorouracil
Paclitaxel
Pertuzumab
Trastuzumab