Overview

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Status:
Withdrawn
Trial end date:
2020-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate in a step-wise approach the disease drug-drug interaction (DDI) potential for vedolizumab to indirectly affect the exposure of cytochrome P-450 (CYP) substrate drugs by modulating pro-inflammatory cytokines in participants with ulcerative colitis (UC) or Crohn's disease (CD) who are treated with vedolizumab.
Phase:
Phase 4
Details
Lead Sponsor:
Takeda
Treatments:
Caffeine
Dextromethorphan
Losartan
Midazolam
Omeprazole
Vedolizumab