Overview Phase I, Dosage-finding and PK Study of IV Topotecan and Erlotinib With Refractory Solid Tumors Status: Completed Trial end date: 2009-08-01 Target enrollment: Participant gender: Summary The purpose of this research study is to determine the best dose of the combination of two approved drugs, intravenous topotecan and oral erlotinib. Phase: Phase 1 Details Lead Sponsor: Accelerated Community Oncology Research NetworkCollaborators: Genentech, Inc.GlaxoSmithKlineTreatments: Erlotinib HydrochlorideTopotecan