Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II)
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to determine if AZD8931 can improve the efficacy of
standard chemotherapy for the treatment of advanced breast cancer. This study will be
conducted in 2 parts: the first part (phase I) will determine a dose of AZD8931 that can be
safely administered with paclitaxel chemotherapy. The second part (phase II) will determine
the efficacy and safety of AZD8931 in combination with paclitaxel chemotherapy in breast
cancer.