Overview

Phase I-II Study of Intratumoral Urelumab Combined With Nivolumab in Patients With Solid Tumors

Status:
Not yet recruiting
Trial end date:
2023-01-30
Target enrollment:
Participant gender:
Summary
Open label, phase I-II study to evaluate the safety and activity of intratumoral urelumab combined with systemic nivolumab in patients with advanced solid tumors. Serial tumor and blood samples will be obtained during the study to characterize the changes induced by treatment in the tumor microenvironment, as well as predictive biomarkers of response.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Clinica Universidad de Navarra, Universidad de Navarra
Treatments:
Antibodies, Monoclonal
Nivolumab