Overview

Phase I/II Study of SRP-4053 in DMD Patients

Status:
Completed
Trial end date:
2019-03-25
Target enrollment:
Participant gender:
Summary
This is a first-in-human, multiple-dose 2-part study to assess the safety, tolerability, efficacy, and pharmacokinetics of SRP-4053 in Duchenne muscular dystrophy (DMD) patients with deletions amenable to exon 53 skipping.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Sarepta Therapeutics
Sarepta Therapeutics, Inc.
Collaborators:
Catholic University of the Sacred Heart
Consultants for Research in Imaging and Spectroscopy
Great Ormond Street Hospital for Children NHS Foundation Trust
Institut de Myologie, France
Royal Holloway University
Sysnav
University College, London
University of Newcastle Upon-Tyne