Overview Phase I/II Trial of Regorafenib, Hydroxychloroquine, and Entinostat in Metastatic Colorectal Cancer Status: Completed Trial end date: 2020-06-01 Target enrollment: Participant gender: Summary The main purpose of this study is to find the best dose of hydroxychloroquine (HCQ) when given in combination with regorafenib and entinostat. Phase: Phase 1/Phase 2 Details Lead Sponsor: Abramson Cancer Center of the University of PennsylvaniaTreatments: EntinostatHydroxychloroquine