Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
OBJECTIVES:
I. Evaluate the toxicity of amifostine in patients with bone marrow failure related to
Fanconi's anemia.
II. Determine the efficacy of this treatment regimen in this patient population.
III. Evaluate the effect of this treatment regimen on bone marrow progenitor cell
proliferation and peripheral blood mononuclear cell apoptosis in these patients.