Overview

Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma

Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
This is a trial for patients affected by metastatic or relapsed osteosarcoma which progressed after first or further line treatments. In this trial, all patients will be treated until progression or unacceptable toxicity with sorafenib and everolimus. The treatment with sorafenib and everolimus aimed to obtain a 50% rate of patients free from further progression of the disease after 6 months from study entry.
Phase:
Phase 2
Details
Lead Sponsor:
Italian Sarcoma Group
Treatments:
Everolimus
Niacinamide
Sirolimus
Sorafenib