Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
Status:
Terminated
Trial end date:
2019-12-09
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to test an experimental treatment method for recurrent
or progressive brain tumors in children aged from 0-22 years. The use of methotrexate and
chemotherapy (topotecan and cyclophosphamide) is experimental in this study. This means that
their use by themselves or together has not been approved by the U.S. Food and Drug
Administration for this usage.