Phase II Study of Radiation Therapy and Vismodegib for Advanced Head/Neck Basal Cell Carcinoma
Status:
Completed
Trial end date:
2019-09-10
Target enrollment:
Participant gender:
Summary
Chemotherapy, radiation therapy, and surgery are standard treatments for basal cell carcinoma
at most institutions. The purpose of this study is to determine whether adding vismodegib to
radiation (chemoradiotherapy) is safe and tolerable. The purpose of this study is to assess
the safety and tolerability of combined radiation therapy and vismodegib. This combination
may increase the chances of the tumors being destroyed or unable to spread to other parts of
the body in people with locally advanced basal cell carcinoma of the head and neck.