Overview

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Status:
Completed
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find out what effects, good and/or bad, sunitinib has on patients and their tumors. At this time, no drugs are routinely used to treat meningioma, hemangioblastoma or hemangiopericytoma. Only surgery and radiation therapy are known to be useful. Sunitinib is a drug approved for advanced kidney cancer. Sunitinib is also being studied for other tumors. It may be useful in the treatment of brain tumors because it can prevent formation of new blood vessels that allow tumor cells to survive and grow.
Phase:
Phase 2
Details
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Collaborators:
Dana-Farber Cancer Institute
Pfizer
University of Pittsburgh
University of Virginia
Treatments:
Cytochrome P-450 CYP3A Inducers
Cytochrome P-450 CYP3A Inhibitors
Sunitinib