Overview

Phase III Randomized Clinical Trial Comparing Post-Transplant Cyclophosphamide (PTCy) to Standard Care (SoC) for Acute Leukemia

Status:
Recruiting

Trial end date:
2025-12-29

Target enrollment:

Participant gender:

Summary

This randomized clinical trial will evaluate two approaches of GvHD prophylaxis; the standard of care GVHD prophylaxis regimen (methotrexate/calcineurin inhibitors) and post-transplant cyclophosphamide with calcineurin inhibitors for their efficacy as a new GVHD prophylaxis strategy.

Phase:

Phase 3

Details

Lead Sponsor:

King Faisal Specialist Hospital & Research Center

Treatments:

Calcineurin Inhibitors
Cyclophosphamide
Methotrexate