Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus
Status:
Completed
Trial end date:
1999-02-01
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Compare the efficacy, onset of clinical anticonvulsant activity, and
complications of diazepam and lorazepam given intravenously as prehospital therapy to
patients in status epilepticus.
II. Determine the effect of prehospital therapy on the incidence of status epilepticus at the
subsequent emergency department admission.
III. Establish whether prehospital therapy alters hospital management of these patients and
ultimately affects patient outcome.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)