Phase IV, 9 Weeks Comparison Between MICARDIS 80 mg and Amlodipine 10 mg on Biological PPAR Gamma Activities
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The objective of the study is to compare PPAR activities (increase of adiponectin level)
between MICARDIS and amlodipine after 6 weeks of treatment in hypertensive patients with
metabolic syndrome. Moreover, this study will compare serum level of inflammatory markers of
the metabolic syndrome after 6 weeks of treatment.
An ancillary study performed in one center will assess adipocyte differentiation (PPAR gamma
stimulation) in 30 subjects (15 per arm).