Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
Status:
Recruiting
Trial end date:
2025-01-01
Target enrollment:
Participant gender:
Summary
The overall goal of this project is to collect initial human data on the effects of novel
compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early
efficacy signals (subjective effects on negative affect, craving, and opioid withdrawal) in
OUD subjects currently in MOUD treatment with buprenorphine.