Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus

• Status: Completed
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

Single center, open label crossover study with 2 treatment phases in healthy volunteers.

The potential of phenotypic drug probes to predict drug-drug interactions between tacrolimus, voriconazole and rifampin will be assessed.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universitaire Ziekenhuizen Leuven
• Treatments: Rifampin; Tacrolimus; Voriconazole

Criteria

Inclusion Criteria:

• Male

• Age over 18 years

• Written informed consent

Exclusion Criteria:

• Female

• Medical comorbidities

• Use of concomitant medication