Phenylephrine Versus Norepinephrine in Ophthalmic Surgery
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
In ophthalmic surgery the specific anaesthesiological challenges necessitate the
administration of a combination of relatively high doses of hypnotics and analgetics. In
order to preserve adequate organ perfusion, there is often a need to administer
pharmacological agents for haemodynamic support. Depending on the experience of the
anaesthetist a continuous infusion of phenylephrine or norepinephrine is used. It is
currently not known which of these agents has the most favorable haemodynamical profile.
Haemodynamic parameters (continuous blood pressure, cardiac index, stroke volume and systemic
resistance), peripheral tissue oxygenation and cerebral tissue oxygenation will be monitored
noninvasively using the Nexfin® , Inspectra®, and Foresight® and O2C® monitoring devices.