Phenylephrine or Norepinephrine for a Better Hemodynamic Stability

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

A prospective, double-blinded study. The present study consisted in applying Stroke volume variation fluid guided therapy to old patients (65 years old) undergoing radical resection of colon surgery. The aim of this study is to compare the effects of norepinephrine and phenylephrine in treating perioperative hypotension, and to find the safest and most effective vasopressor for elderly.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The Second Affiliated Hospital of Dalian Medical University
• Treatments: Adrenergic Agonists; Norepinephrine; Oxymetazoline; Phenylephrine

Criteria

Inclusion Criteria:

• Operation time should be equal or greater than 2h,

• Patients older than 65 years old,

• ASA Ⅱ or Ⅲ.

Exclusion Criteria:

• Clear arrhythmia,

• Need to apply PEEP,

• Peripheral vascular disease and arterial catheter contraindications.