Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to determine if a medication called phenylephrine, which helps to
control blood pressure, is more effective as a continuous intravenous (IV) infusion compared
to continuous IV norepinephrine in maintaining blood pressure during a spinal anesthetic for
a cesarean delivery. Good blood pressure control has been shown to decrease nausea and
vomiting during and after cesarean delivery under spinal anesthesia. For elective cesarean
delivery, all participants will receive spinal anesthesia with a local anesthetic and
morphine (provides long term pain control after cesarean delivery). This study plans to
enroll 80 pregnant research subjects 18 years and above. Patients will be randomly assigned
according to a computer generated system to be in one of two groups.