Overview

Photodynamic Therapy Alone Versus Combined With Intravitreal Bevacizumab for Age-related Macular Degeneration

Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to compare 12-month results of two single initial treatments-photodynamic therapy with verteporfin alone and this therapy combined with intravitreal bevacizumab-for neovascular age-related macular degeneration, not including patients with polypoidal choroidal vasculopathy who were presumed to have age-related macular degeneration.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Kumamoto University
Treatments:
Bevacizumab
Criteria
Inclusion Criteria:

- choroidal neovascularization caused by age-related macula degeneration

- no previous treatment

- a follow-up at least 12 months

- a baseline visual acuity ranging from a letter score of 0 to 70 on the Early Treatment
Diabetic Retinopathy Study chart

Exclusion Criteria:

- choroidal neovascularization caused by other eye diseases

- ocular surgery within the past 3 mouths

- history of uveitis

- intraocular pressure higher than 25 mmHg, or glaucoma

- history of systemic or ocular thromboembolic events.