Physical Exercise Versus Rosiglitazone in CAD and Prediabetes

• Status: Completed
• Trial end date: 2007-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to prospectively assess the relative benefits of either treatment with rosiglitazone or physical exercise on endothelial function in patients with impaired fasting glucose or impaired glucose tolerance and coronary artery disease (CAD).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Leipzig
• Treatments: Rosiglitazone

Criteria

Inclusion Criteria:

• impaired fasting glucose or impaired glucose tolerance

• angiographic evidence of coronary artery disease

Exclusion Criteria:

• diabetes mellitus type I or II

• preexisting antidiabetic medication

• unstable angina

• indication for coronary bypass surgery

• significant left main disease

• myocardial infarction within preceding 3 months

• ejection fraction < 40%

• significant heart valve disease

• severe metabolic disorders

• severe disorders in lipoprotein metabolism

• thyroid disorders

• alcohol or drug abuse

• pregnancy

• participation in another trial