Overview

Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock: a Phase 0 Trial.

Status:
Recruiting

Trial end date:
2022-02-01

Target enrollment:

Participant gender:

Summary

This trial is an open-label, single center, Phase 0 trial that will enroll up to 25 participants with circulatory shock after cardiac surgery. Participants will be administered a topical sublingual nitroglycerin solution and assessed for changes microcirculatory blood flow using incident dark field microscopy.

Phase:

Early Phase 1

Details

Lead Sponsor:

University of Pennsylvania

Treatments:

Nitroglycerin