Physiologic Interactions Between the Adrenal- and the Parathyroid Glands

• Status: Completed
• Trial end date: 2017-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

To investigate possible physiologic interactions between the adrenal- and the parathyroid glands in patients with secondary hyperparathyroidism.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Aarhus
• Treatments: Cholecalciferol; Valsartan; Vitamin D

Criteria

Inclusion Criteria:

• Secondary hyperparathyroidism due to Vitamin D deficiency

Exclusion Criteria:

• Cardiovascular disease

• Renal failure

• Liver failure

• Treatment with antihypertensive medication or diuretics

• Treatment with lithium, NSAID or glucocorticoids

• Calcium supplement more than 500 mg per day or Vitamin D supplement more than 25 microgram per day

• Medical treatment for osteoporosis

• Systolic blood pressure below 120 mmHg

• Hypercalcaemia (more than 1,33mmol/L)

• Use of solarium or planned trip to countries, that might increase the endogenous vitamin D synthesis

• Allergic reaction to ACEi or ARBs.