Overview

Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Status:
Enrolling by invitation
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
In this study, we will test the feasibility of N-of-1 trials for deprescribing beta-blockers in patients with Heart Failure with Preserved Ejection Fraction. To achieve this objective we will conduct 16 4-period N-of-1 trials (on vs. off) and subsequently interview participants to better understand feasibility and pragmatism. The N-of-1 trials will be iteratively refined in real-time based on this feedback.
Phase:
Phase 4
Details
Lead Sponsor:
Weill Medical College of Cornell University
Collaborator:
National Institute on Aging (NIA)
Treatments:
Acebutolol
Adrenergic beta-Antagonists
Atenolol
Betaxolol
Bisoprolol
Carvedilol
Labetalol
Metoprolol
Nadolol
Nebivolol
Penbutolol
Pindolol
Propranolol
Sotalol