Overview

Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging

Status:
COMPLETED
Trial end date:
2024-11-06
Target enrollment:
Participant gender:
Summary
This is a pilot, non-randomized, two-cohort interventional study in patients who meet the inclusion criteria, using an FDA- approved androgen deprivation agent for a 3 or 6-week course of treatment prior to standard-of-care RALP with PLND. The intent of the study is to determine the effect of ADT on PSMA expression as measured by PSMA-PET scan. A second PSMA-PET scan will be performed after ADT for either 3 or 6 weeks, depending on cohort, prior to RALP and PLND.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
Urology Clinics of North Texas
Collaborators:
Blue Earth Diagnostics
Texas Health Resources
Treatments:
relugolix