Pilot Study Testing a New Strategy for Management of Spontaneous Preterm Birth

• Status: Unknown status
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Preterm birth is a major public health problem, and actual treatments are not very efficient. The purpose of this study is to test the efficiency of a combined use of Montelukast and Nifedipine to treat preterm labor. Investigators aim to reduce uterine contractions more efficiently than with the use of Nifedipine only.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Université de Sherbrooke
• Treatments: Montelukast

Criteria

Inclusion Criteria:

• women with 24-34 weeks of pregnancy

• indication for tocolysis

Exclusion Criteria:

• preterm labor before 26 or after 34 weeks of pregnancy

• minor patients

• patients with other obstetrical pathology

• twin pregnancies

• fetal distress

• severe congenital fetal malformation

• anti-phospholipid syndrome

• lupus

• gestational diabetes

• nephropathy

• congenital heart disease

• obvious causes of infection associated with prematurity

• patients with viral infections (HIV, hepatitis)

• patients already treated with Montelukast