The aim of this pilot study for the NorCAPITAL trial is to investigate the feasibility and
safety of the drug clonidine in adolescent chronic fatigue syndrome (CFS). Specifically, the
investigators wanted to assess appropriate dosage in relation to a) plasma concentration
levels of clonidine, b) orthostatic cardiovascular responses (the pulse and blood pressure
responses when rising up), and c) reports of possible adverse effects.
A possible beneficial effect of clonidine in adolescent CFS will be investigated in
NorCAPITAL, which is a randomized, placebo-controlled, double blind trial.