Pilot Study for the Tight K Study

• Status: Completed
• Trial end date: 2018-05-29
• Target enrollment: 0
• Participant gender: All

Summary

The primary purpose of this pilot study will be feasibility of recruitment. However, in order to further inform a full randomised controlled trial (RCT), information on the incidence of atrial fibrillation (AF) and other arrhythmias, hospital length of stay, resource use and morbidity will be collected.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Barts & The London NHS Trust; Queen Mary University of London
• Collaborator: London School of Hygiene and Tropical Medicine

Criteria

Inclusion Criteria:

1. All patients undergoing isolated elective coronary artery bypass graft (CABG)

Exclusion Criteria:

1. Age less than 18 years

2. Previous AF

3. Concurrent patient involvement in another clinical study assessing post-operative interventions

4. On-going infection/sepsis at the time of operation

5. Pre-op high-degree atrioventricular (AV) block

6. Pre-op serum K+ greater than 5.5 mEq/L

7. Current or previous use of medication for the purposes of cardiac rhythm management

8. Dialysis dependent end stage renal failure