Pilot Study of Bupropion for Smoking Cessation in Postpartum Non-breastfeeding Women

• Status: Terminated
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this small preliminary study is to determine whether it is feasible to recruit women smokers who have just delivered a baby and are not breastfeeding into a study that would test whether starting bupropion, a smoking cessation medication, after a baby's birth helps a postpartum woman to stop smoking.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Massachusetts General Hospital
• Collaborator: Robert Wood Johnson Foundation
• Treatments: Bupropion

Criteria

Inclusion Criteria:

Postpartum women who:

• Smoked >1 cigarette in last month of pregnancy

• Deliver a baby at Brigham and Women's Hospital in Boston, MA

• Do not breastfeed or plan to breastfeed.

• Want to attempt to stop smoking

Exclusion Criteria:

• Age <18 years;

• Current use of bupropion or antidepressant;

• Current major depression or other severe psychiatric illness (e.g., schizophrenia, mania);

• Contraindication to use of bupropion;

• Illegal substance use in past 6 months;

• >1 drink/day of alcohol during pregnancy;

• Newborn with major congenital anomaly or <25 weeks' gestation;

• Inability to speak or read English;

• No telephone.