Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer Patients
Status:
Terminated
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
Many women with breast cancer who are treated with aromatase inhibitor medications develop
difficulty sleeping and fatigue during treatment. Some examples of aromatase inhibitor
medications include anastrozole (Arimidex), exemestane (Aromasin), and letrozole (Femara).
Frequently, sleeping pills do not work very well to improve sleep. Cyclobenzaprine (Flexeril)
is a medication that was originally developed to treat muscle spasms. It may also improve
sleep in patients with chronic pain disorders, such as fibromyalgia. In this study we are
testing to see if cyclobenzaprine at bedtime will help improve sleep in women treated with
aromatase inhibitors.