Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.
Status:
Unknown status
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
A Pilot study to evaluate the safety and the efficacy of endotracheal instillation of
pulmonary surfactant, with or without topical steroid (Budesonide), as a prophylactic
treatment for Bronchopulmonary Dysplasia (a form of chronic lung disease) in extremely low
birth weight infants. Cytokines (a group of inflammatory mediators) are measured in the
tracheal aspirate before and after instillation of the study drugs.