Pilot Study on Withdrawal of Spironolactone Among Heart Failure With Improved Ejection Fraction
Status:
Active, not recruiting
Trial end date:
2022-06-30
Target enrollment:
Participant gender:
Summary
The study is a randomized controlled pilot trial to evaluate whether withdrawal of
spironolactone is safe and associated with re-deterioration of left ventricular function in
patients with heart failure with improved ejection fraction. The aim of current trial is to
test the hypothesis that withdrawal of spironolactone would not be associated with relapse of
significant clinical deterioration of left ventricular systolic function.