Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of Migraine
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
Subjects enrolled at 2 investigative sites will complete 3 visits. Following Visit 1, during
a 1-month Baseline Period, subjects will treat with their usual medication and document any
warning signs (Prodrome pre-headache) that a migraine will occur. Following randomization
(like a flip of the coin) at Visit 2, subjects will treat daily with topiramate or during
Prodrome with frovatriptan. Subjects complete a 2-month Treatment Period before exit at Visit
3.This study will compare the effectiveness of daily treatment vs. treatment during the
pre-headache phase for prevention of migraine.