Placebo Effect in the Treatment of Atopic Dermatitis

• Status: Completed
• Trial end date: 2015-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The study is initiated in the indication of atopic dermatitis to study the impact of placebo in the treatment of pruritus. Classical conditioning and expectation via instructions/anticipation maintain the effect of placebo.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Margitta Worm
• Collaborators: University of Hamburg; University of Hamburg-Eppendorf
• Treatments: Dimethindene

Criteria

Inclusion Criteria:

• SCORAD-Score < 50 points

• basic experimental pruritus >= 3 points on a numeric rating scale

• no acute eczema on their forearms

• no systemic treatments for skin diseases for at least four weeks

• no topical treatment on their arms for at least two weeks

Exclusion Criteria:

• intake of antihistamines

• pregnancy and lactation

• serious dysfunctions of the liver, kidneys or thyroid

• prostatic hyperplasia

• patients with tumors, major cardiovascular diseases, immunosuppression

• glaucoma