Placebo-controlled RCT of Botulinum Toxin A as a Treatment for Provoked Vestibulodynia
Status:
Completed
Trial end date:
2019-06-01
Target enrollment:
Participant gender:
Summary
Women with provoked vestibulodynia (PVD) suffer from severe dyspareunia and often present a
hyperactivity of the pelvic floor muscles (PFM) which maintain the dyspareunia. The rationale
for the study is that for women with PVD who don't succeed to restore the function of the PFM
by physiotherapy, Botulinum Toxin A (BTA) could be an optional treatment by decreasing the
high muscle tonus and thus possibly reduce the coital pain.
Phase:
Phase 3
Details
Lead Sponsor:
Karolinska Institutet
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA