Plant Sterols Effect on Previous Statin Therapy

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of plant sterols associated with ezetimibe in LDL-cholesterol levels in coronary patients previously on statin therapy

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jose Rocha Faria Neto
• Treatments: Ezetimibe; Hydroxymethylglutaryl-CoA Reductase Inhibitors

Criteria

Inclusion Criteria:

• Patients with previous myocardial infarction, stroke or coronary angiography demonstrating significant coronary disease.

• Subjects under statin treatment with a fixed dosage for the previous three months before randomization, and did not reached LDL less than 70mg/dl.

Exclusion Criteria:

• Subjects already taking ezetimibe and/or plant sterols

• Younger than 18 years

• Presence of any contraindication to statin

• Pregnant women or breast-feeding women or

• Patients with previous history of statin hypersensibility