Platelet Augmentation Using C. Papaya Leaf Extract in Live Donor Liver Transplantation
Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
This project is a pilot randomized controlled trial aimed at investigating the potential of
Carica Papaya Leaf Extract, available in a marketed pill formulation, in increasing platelet
counts in live donor liver transplant recipients. Carica Papaya leaf extract has shown
positive results in increasing platelet counts in various medical conditions such as Dengue,
Immune thrombocytopenic purpura and chemotherapy induced thrombocytopenia. Thrombocytopenia
i.e. low platelet counts are a common occurrence in patients with chronic liver disease
undergoing live donor liver transplant. It has been observed in previous studies that live
donor liver transplant recipients who have persistent thrombocytopenia have significantly
worse outcomes as compared to patients who have higher platelet counts. Positive results in
this study lead to further studies in assessing the impact of platelet augmentation in live
donor liver transplant recipients.