Platelet Rich Plasma Injection in Pilon Fractures

• Status: Completed
• Trial end date: 2019-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients who sustain broken ankles have a very high risk of developing arthritis soon after injury (within 2 years). This arthritis can cause increased pain and a decrease level of function, especially if the injury occurs at an early age. During and shortly after ankle injury, there is an inflammatory chemical process that takes place in the ankle that can cause damage to the cartilage in the ankle joint. The investigators want to use what is called Platelet Rich Plasma (PRP), which is produced from a small amount of the patient's own blood, to inject into the injured ankle to see if they can decrease the inflammation that happens after the injury and to see if they can decrease arthritis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Missouri-Columbia

Criteria

Inclusion Criteria:

• Closed unilateral pilon fracture

Exclusion Criteria:

• Patients who are younger than 18 years of age

• Open pilon fracture

• Patients with contralateral lower extremity injury

• Patients unable to comply with the follow-up appointments

• Patients who had previous ankle injury to the currently injured ankle

• Patients who are pregnant

• Prisoners