Platelet Rich Plasma and Wound Healing After Cesarean Section

• Status: Completed
• Trial end date: 2020-12-30
• Target enrollment: 0
• Participant gender: Female

Summary

Objective: To assess the effect of autologous Platelet Rich Plasma (PRP) on wound healing and pain perception in high risk women undergoing cesarean sections in a low resource setting.

Methods: This was a randomized controlled trial of 200 women who attended the outpatient clinic of Menoufia University Hospital for elective cesarean surgery. The women were randomly assigned to two groups. The intervention group received PRP after surgery, whereas the control group received the usual care. Outcomes included Redness, Edema, Ecchymosis, Discharge, Approximation (REEDA) scale, Vancouver scar scale (VSS), and the visual analog scale (VAS).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University

Criteria

Inclusion Criteria:

• Body mass index (BMI) > 30 kglcm2

• prior cesarean section

• pregestational or gestational diabetes

• hypertensive disorders of pregnancy

• placenta Previa

• twin pregnancy

• anemia

• corticosteroid medication

Exclusion Criteria

• • chronic pain disorders

• hepatitis

• thrombocytopenia

• coagulation disorders