Overview

Platelet-dependent Thrombosis: a Placebo-controlled Trial of Antiplatelet Therapy (Clopidogrel)

Status:
Completed
Trial end date:
2012-04-01
Target enrollment:
Participant gender:
Summary
Patients with diabetes are more likely to develop furring of their coronary arteries and present with angina and heart attacks. Furthermore, after such an event, they have poorer outcomes (higher rates of death) and survivors are more likely to have recurring symptoms. Using a novel "clotting chamber" the investigators have shown that patients with diabetes are more likely to develop blood clots. This study will look at the role of different blood thinning medications in patients with diabetes. If successful, the investigators will provide evidence to conduct large clinical studies to look at the role of additional blood thinning medication in reducing heart attacks and strokes in patients with diabetes.
Phase:
Phase 4
Details
Lead Sponsor:
Newcastle-upon-Tyne Hospitals NHS Trust
Collaborators:
British Heart Foundation
University of Newcastle Upon-Tyne
Treatments:
Aspirin
Clopidogrel
Ticlopidine