Polydeoxyribonucleotide (PDRN) for Cuff Regeneration

• Status: Recruiting
• Trial end date: 2023-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is to evaluate the effect of polydeoxyribonucleotide (PDRN) for healing and fatty degeneration of rotator cuff. The investigators will enroll 130 patients with rotator cuff tear who will undergo arthroscopic rotator cuff repair. 130 patients will be classified into two group. One group (PDRN) will be injected at the repaired cuff with 3cc polydeoxyribonucleotide just after surgery and be injected with another 3ml polydeoxyribonucleotide under ultrasound guidance 2 weeks after the surgery. The other group (CONTROL) will be injected with 3ml normal saline in the same manner.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chuncheon Sacred Heart Hospital
• Collaborator: Ministry of Science and ICT

Criteria

Inclusion Criteria:

• definite rotator cuff tear on preoperative MRI, which needs repair

• acceptance of arthroscopic surgery including rotator cuff repair

Exclusion Criteria:

• history of ipsilateral shoulder operation or fracture

• concomitant neurological disorder around the