Polymorphism of beta2-adrenoceptor and Regular Use of Formoterol in Asthma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Polymorphism at codon 16 of the beta2-adrenoceptor (beta2-AR) affects the responsiveness to
salmeterol in asthmatics. Data concerning formoterol are more controversial in literature.
The aim of this study was to verify whether homozygote for arginine-16 (ArgArg16) and
homozygote for glycine-16 (GlyGly16) genotypes differently influence the long-term
responsiveness to formoterol.