Overview

Polymorphism of the Cytochrome P450-system in Renal Transplants

Status:
Completed
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
In this study the researchers want to investigate genetic polymorphisms of cytochrome 450 enzymes and the multiple drug resistance (MDR) gene in renal transplant patients to look for differences in dosing of immunosuppressive drugs (tacrolimus, sirolimus, everolimus, cyclosporine A). All patients who receive one of these drugs can be included and drug blood trough levels, dosing and genetics are compared.
Details
Lead Sponsor:
University Hospital Schleswig-Holstein
University of Schleswig-Holstein
Collaborator:
University of Kiel
Treatments:
Cyclosporine
Cyclosporins
Everolimus
Sirolimus
Tacrolimus