Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia
Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
This study is based on the hypothesis that the pharmacokinetics of antibiotics in children is
different from adults. Cephalosporins and macrolide antibiotics are the common drugs for
children with community acquired pneumonia, the investigators aim to study the population
pharmacokinetics of cephalosporins and macrolide antibiotics in children receiving the drug
for treatment of community acquired pneumonia, and to correlate it with treatment
effectiveness and incidence of adverse effects.
Potential Impact: This novel knowledge will allow better and more rational approaches to the
treatment of community acquired pneumonia. It will also set the foundation for further
studies that will be able to test improved therapies that may increase treatment response in
vulnerable children.