Population Pharmacokinetics of Fentanyl in Patients Undergoing Living Donor Liver Transplantation

• Status: Completed
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study was to characterize pharmacokinetics of fentanyl during and after Living Donor Liver Transplantation (LDLT), using population pharmacokinetic analysis with non linear mixed effects modeling.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Asan Medical Center
• Collaborator: Ministry of Health & Welfare, Korea
• Treatments: Fentanyl

Criteria

Inclusion Criteria:

• Patients between 19 - 65 years of age

• Over 45kg of weight

• Written Informed consent

• Patients receiving a liver graft from living donor (ASA PS III or IV)

Exclusion Criteria:

• Patients with renal dysfunction

• Patients with Fulminant hepatic failure

• Patients participated other clinical trials within 2 months

• Unable or Unwilling to give informed consent

• Abnormal test results with clinical significance