Positive Airway Pressure Under Apnoeic Oxygenation With Different Flow Rates in Nasal Cannula Therapy

• Status: Completed
• Trial end date: 2019-03-31
• Target enrollment: 0
• Participant gender: All

Summary

The main objective of this explorative observational study is to investigate the pressures in infraglottic airway and the pharynx provided by THRIVE , using flows ranging from 1l/min to 80 l/min, in patients hospitalized for elective surgical procedure; to investigate the correlation between airway pressure and nasal oxygen flow.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital Inselspital, Berne
• Collaborator: University of Bern

Criteria

Inclusion Criteria:

• > 18 years

• Written informed consent

• Undergoing elective surgery

• Requiring general anesthesia

• ASA 1-3 (American Society of Anesthesiologists)

Exclusion Criteria:

• Any Indication for fibre optic intubation

• Expected impossible mask ventilation

• Known coronary heart disease

• Known heart failure, NYHA classification( New York Heart Association ) ≥ 2

• Peripheral occlusive arterial disease, Fontaine ≥ 2b

• BMI > 30kg/m2 and BMI < 16kg/m2

• Hyperkalaemia (K > 5.5 mmol/l)

• Known COPD (Chronic obstructive pulmonary disease) Gold classification ≥ 2

• Known pulmonary arterial hypertension, systolic > 35mmHg

• Known obstructive sleep apnoea syndrome in need of therapy

• High risk of aspiration

• Increased intracranial pressure

• Intracranial surgery

• Limited knowledge of German language

• Absent power of judgement

• Pregnancy (pregnancy test before inclusion)

• Neuromuscular disorder

• Known or suspected cervical spine instability

• Nasal obstruction, impossibility of nasal ventilation (both sides patent)

• Allergies or contra-indications to one or more of the used anaesthesia agents